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This does not make any sense to us as to why this could happen. There is nothing in Sierra Chart which will change one of these Inputs to reference another chart. It simply does not exist. The only thing that does exist is to change the input internally to 0 to remove the reference and this is explained here:
Unable to Change the Bar Time Period for Charts

And in any case, simply change the references to what they should be.

What specific TPO Profile Chart Study Inputs changed? This does not make any sense to us either. Not sure what setting you are referring to which would stop the reloading. This does not make sense to us either. But this is beside the point.

The best way to approach the problem is to read the documentation for the studies that you are using and work through what you need to do from the very start. Here is the relevant documentation:
http://www.sierrachart.com/index.php?page=doc/TechnicalStudiesReference.html


However, when it comes to referencing other charts make sure you do not create the condition which is described in help topic 30.3:
https://www.sierrachart.com/index.php?page=doc/helpdetails30.html#h30.3

As long as you avoid that, you will not have any difficulties.